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Urine analysis (physical, chemical and microscopic examination of urine).pdf by Ayat Samy, has 64 slides with 11 views.urinalysis physical examination of urine chemical examination of urine
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Prescription Writing for Glaucoma: A Clinical Guide by Shivankan Kakkar, has 14 slides with 18 views.This presentation provides a comprehensive guide to prescription writing for glaucoma, covering primary open-angle glaucoma, acute angle-closure glaucoma, and chronic angle-closure glaucoma. It includes clinical case scenarios, drug selection, dosage recommendations, administration routes, contraindications, and patient education strategies. A valuable resource for medical students and healthcare professionals looking to refine their prescribing skills.
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pyloric stenosis n.pptx child health nursing by Pooja Rani, has 17 slides with 49 views.pyloric stenosis
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DIFFERENTIAL DIAGNOSIS OF BASAL & PARAMEDICAL PROFESSES, PULMONARY DISSEMINAT... by Ankur Verma , has 12 slides with 15 views.Explore the differential diagnosis of basal and paramedical processes, pulmonary disseminations, and pulmonary infiltrates, focusing on clinical features, imaging findings, and key distinguishing factors for accurate diagnosis.
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Understanding-Seizures-and-Epilepsy-Management.pptx by Dr Ankush goyal, has 8 slides with 237 views.Epilepsy and Its Management Introduction Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures. It affects millions of people worldwide, cutting across all age groups and ethnicities. Seizures result from excessive and abnormal cortical nerve cell activity in the brain, leading to temporary changes in movement, sensation, behavior, or consciousness. This document provides a comprehensive overview of epilepsy, including its causes, classification, symptoms, diagnosis, and management strategies. Causes of Epilepsy Epilepsy can arise due to multiple factors, including genetic predisposition, brain injuries, infections, or developmental disorders. Some common causes include: Genetic Factors: Certain types of epilepsy have a hereditary component, suggesting that genetic mutations may contribute to its development. Brain Trauma: Head injuries from accidents or sports activities can lead to epilepsy. Stroke and Vascular Diseases: Stroke, which reduces oxygen supply to the brain, is a leading cause of epilepsy in older adults. Infections: Conditions such as meningitis, encephalitis, and neurocysticercosis can trigger epilepsy. Developmental Disorders: Disorders such as autism and neurofibromatosis have been linked to epilepsy. Tumors and Structural Abnormalities: Brain tumors and congenital malformations can also lead to epileptic seizures. Classification of Epilepsy The International League Against Epilepsy (ILAE) classifies epilepsy based on the nature of seizures and their origin in the brain: Focal (Partial) Seizures: Originate in one part of the brain and can be simple (without loss of consciousness) or complex (with impaired consciousness). Generalized Seizures: Involve both hemispheres of the brain and include types such as absence, tonic-clonic, myoclonic, and atonic seizures. Unknown Onset Seizures: When the starting point of the seizure is unclear. Epilepsy Syndromes: Specific syndromes such as Lennox-Gastaut syndrome, Dravet syndrome, and Juvenile Myoclonic Epilepsy have distinct features and management strategies. Symptoms of Epilepsy The clinical manifestations of epilepsy depend on the type of seizure and the brain region involved. Symptoms may include: Temporary confusion or staring spells Uncontrollable jerking movements (convulsions) Loss of consciousness or awareness Sensory disturbances such as tingling or hallucinations Emotional changes, anxiety, or déjà vu Diagnosis of Epilepsy A thorough medical evaluation is necessary to diagnose epilepsy accurately. The diagnostic process includes: Medical History and Physical Examination: A detailed history of seizure episodes, triggers, and associated conditions is crucial. Electroencephalogram (EEG): Measures electrical activity in the brain and identifies abnormal patterns suggestive of epilepsy. Neuroimaging (MRI, CT Scan): Detects structural abnormalities, tumors, or brain injuries. Blood Tests: Helps rule out metabolic or i
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PARKINSON’S USMLE style question by dr ankush goyal by Dr Ankush goyal, has 43 slides with 292 views.Parkinsonism refers to a clinical syndrome characterized by a combination of motor and non-motor symptoms that resemble Parkinson’s disease (PD). It results from dysfunction in the basal ganglia, particularly due to dopamine deficiency in the substantia nigra. Key Features of Parkinsonism: 1. Bradykinesia – Slowness of movement with difficulty in initiating and executing voluntary movements. 2. Rigidity – Increased muscle tone, presenting as either: Lead-pipe rigidity (uniform resistance) Cogwheel rigidity (intermittent resistance with a ratchet-like quality) 3. Tremor – Resting tremor, typically "pill-rolling" (4-6 Hz), that improves with movement. 4. Postural Instability – Impaired balance leading to a higher risk of falls. Causes of Parkinsonism: 1. Idiopathic Parkinson’s Disease (PD) – The most common cause, due to progressive degeneration of dopaminergic neurons in the substantia nigra. 2. Drug-Induced Parkinsonism – Caused by dopamine-blocking agents (e.g., antipsychotics, metoclopramide, reserpine). 3. Atypical Parkinsonian Syndromes (Parkinson-plus syndromes) – Progressive conditions with additional features beyond classic Parkinsonism, such as: Multiple System Atrophy (MSA) Progressive Supranuclear Palsy (PSP) Corticobasal Degeneration (CBD) Dementia with Lewy Bodies (DLB) 4. Vascular Parkinsonism – Due to multiple small strokes affecting the basal ganglia. 5. Toxic or Metabolic Causes – Includes manganese poisoning, carbon monoxide exposure, Wilson’s disease. 6. Post-Encephalitic Parkinsonism – Rare, seen in survivors of encephalitis lethargica. Diagnosis: Clinical Evaluation – Based on cardinal motor symptoms. Response to Levodopa – Helps differentiate PD from other causes. Neuroimaging (MRI, DaTscan) – Useful in atypical cases. Management: Pharmacological Treatment: Levodopa (with carbidopa) Dopamine agonists (pramipexole, ropinirole) MAO-B inhibitors (selegiline, rasagiline) COMT inhibitors (entacapone) Anticholinergics (for tremors) Non-Pharmacological Treatment: Physiotherapy, speech therapy Deep Brain Stimulation (DBS) in selected cases
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Integumentary System By Baasir Umair.pdf by Baasir Umair Khattak, has 78 slides with 86 views.The integumentary system is the largest organ system of the human body, serving as the body's first line of defense against environmental hazards. It includes the skin, hair, nails, glands, and sensory receptors. This system plays a vital role in protection, thermoregulation, sensation, excretion, and vitamin D synthesis. Understanding its structure and function is crucial for comprehending how the body interacts with its surroundings. Structure of the Integumentary System The integumentary system comprises two main components: The Skin (Cutaneous Membrane) Accessory Structures (Hair, Nails, and Glands) The Skin The skin, also called the cutaneous membrane, consists of three primary layers: 1. Epidermis The epidermis is the outermost layer of the skin, composed of stratified squamous epithelium. It lacks blood vessels and is primarily made of keratinocytes, which produce the protective protein keratin. Other important cells in the epidermis include: Melanocytes – produce melanin, which protects against UV radiation. Langerhans cells – involved in immune response. Merkel cells – associated with sensory neurons for touch perception. The epidermis has five distinct layers (from deep to superficial): Stratum basale (germinativum) – contains basal cells responsible for generating new keratinocytes. Stratum spinosum – provides structural integrity. Stratum granulosum – where keratinization begins. Stratum lucidum – found only in thick skin (palms and soles). Stratum corneum – the outermost layer made of dead keratinized cells. 2. Dermis The dermis is the thicker, connective tissue layer beneath the epidermis. It consists of collagen and elastic fibers, providing strength and flexibility. The dermis has two layers: Papillary Layer – composed of loose areolar connective tissue; contains dermal papillae, capillaries, and sensory receptors. Reticular Layer – made of dense irregular connective tissue; contains sweat glands, hair follicles, and blood vessels. 3. Hypodermis (Subcutaneous Layer) The hypodermis is a layer of adipose and connective tissue that insulates the body, stores energy, and provides cushioning. It connects the skin to underlying muscles and bones. Functions of the Integumentary System The skin performs several essential functions, including: 1. Protection The skin acts as a physical barrier against microorganisms, dehydration, UV radiation, and harmful chemicals. The acid mantle (low pH) of the skin inhibits bacterial growth. 2. Thermoregulation The skin helps maintain body temperature through: Sweating (eccrine and apocrine glands) – evaporative cooling. Vasodilation – blood vessels widen to release heat. Vasoconstriction – blood vessels narrow to retain heat. Goosebumps (arrector pili muscles) – create an insulating layer. 3. Sensation The skin contains specialized sensory receptors: Meissner’s corpuscles – detect light touch. Pacinian corpuscles – sense deep pressure and vibration. Merkel cells –
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78 slides86 views
Trend Academic Studies in Health Sciences by Dr. Nasir Mustafa, has 4 slides with 230 views.Revolutionizing Anatomy Education: The Power of AI-Driven Personalized Learning AUTHOR, Dr. Nasır MUSTAFA (All Sciences Academy)
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Understanding the Impact of Revalidation on UK Healthcare Professionals.pdf by Medical Apprisal, has 4 slides with 140 views.Revalidation UK is a vital process ensuring healthcare professionals maintain high standards, enhancing patient safety and public trust. This mandatory assessment promotes continuous professional development, requiring practitioners to demonstrate competence, adhere to ethical guidelines, and engage in reflective practice. Despite challenges like administrative burdens and balancing clinical duties, revalidation fosters lifelong learning and accountability. Employers and regulatory bodies play a key role in supporting professionals through training, mentorship, and streamlined appraisal processes. As technology advances, revalidation UK will evolve to simplify compliance and enhance accessibility. By embracing revalidation, healthcare professionals contribute to a safer, more effective healthcare system, reinforcing trust and excellence in patient care across the UK.
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Growth and development milestone 7 months .pptx by Abhishek Verma , has 12 slides with 17 views.Growth and developed milestone for a 7 months old children Milestone 7 months At seven months, your baby is becoming more active, curious, and expressive! Many can sit up without support, reach for toys, and even start rocking on their hands and knees, a sign that crawling is coming soon. Their grip is improving, so they enjoy grabbing, shaking, and banging objects together. Socially, they recognize their name, respond to familiar voices, and may show separation anxiety when a parent leaves the room. They love interactive games like peekaboo and enjoy babbling sounds like “ba-ba” and “da-da.” Solid foods are now a regular part of their diet, along with breast milk or formula. They may sleep 12–16 hours a day, including two or three naps. Every baby develops at their own pace, so don’t worry if they’re not hitting every milestone at the same time as others. Enjoy this exciting stage of discovery and growth. Discover the essential growth and development milestones of a 7-month-old baby. Learn about physical, cognitive, emotional, and social developments, including motor skills, sensory awareness, speech progress, and feeding habits. Get expert parenting tips, activities, and guidance to support your baby's healthy development. Stay informed with this comprehensive guide Wondering what milestones your 7-month-old should be reaching? This expert guide covers key physical, cognitive, and social developments, from sitting up and babbling to improved hand-eye coordination. Learn about feeding, sleep patterns, and fun activities to support your baby's growth. Get top parenting tips and insights to ensure your little one thrives! #pediatricnursing #Growthanddevelopment #Growthanddevelopmentalmilestones Growth and development ppt Growth and development milestone slideshare ppt
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Yasser’s Electrocardiographic Palpitations Wave with Bilobed Apical Floating ... by YasserMohammedHassan1, has 36 slides with 61 views.Bilobed Apex heart with Floating Heart syndrome is an innovative cardiovascular and radiological discovery. The Bilobed Apex heart with Floating Heart syndrome with "Yasser’s Electrocardiographic Palpitations Waves" and off-phenomenon post-amiodarone IVB injection are remarkable innovative constellations. "Yasser’s Electrocardiographic Palpitations Waves" was shortly described as a superficial upright wave associated with unusual palpitations. Bilobed Apex heart with Floating Heart has no known cause. It is mostly congenital. The senses of sudden heart stoppage, generalized fatigue, vertigo, acute confusion, generalized body relaxation, a sense of separation from the environment, and a sense of no abnormality within minutes of amiodarone IVB injection are an off phenomenon.
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Good Laboratory Practices (GLP) Ensuring Quality and Compliance.pptx by Dr. Smita Kumbhar, has 53 slides with 252 views.Good Laboratory Practices (GLP): Ensuring Quality and Compliance Good Laboratory Practices (GLP) is a set of principles intended to ensure the quality, integrity, and reliability of non-clinical laboratory studies that support research and regulatory submissions. These guidelines are critical in the pharmaceutical, biotechnological, chemical, and environmental sectors, ensuring that laboratory-generated data are reproducible, credible, and internationally accepted. GLP standards primarily apply to safety studies involving pharmaceuticals, pesticides, food additives, and industrial chemicals. Regulatory agencies, including the USFDA, EMA, and OECD, enforce GLP compliance to maintain scientific rigor and public safety. USFDA GLP Regulations The U.S. Food and Drug Administration (USFDA) established Good Laboratory Practice regulations under 21 CFR Part 58. These regulations outline responsibilities for study directors, testing facilities, and personnel to maintain quality and integrity in non-clinical laboratory studies. The regulations cover various aspects, including study conduct, reporting, and archiving, ensuring consistency and accuracy in laboratory research. Controlling the GLP Inspection Process Regulatory authorities conduct inspections to verify GLP compliance. Laboratories must prepare for inspections by: • Maintaining up-to-date documentation. • Conducting internal audits. • Ensuring personnel training and awareness. • Implementing corrective actions for non-compliance. Regulatory inspections typically assess laboratory infrastructure, personnel competence, study documentation, and adherence to protocols. Laboratories must demonstrate transparency and proactive quality control measures. Documentation in GLP Accurate and comprehensive documentation is crucial in GLP compliance. Key documentation elements include: • Study protocols • Standard operating procedures (SOPs) • Raw data records • Analytical reports • Audit reports • Equipment calibration records • Archiving and retention policies Proper documentation ensures traceability, accountability, and reliability in laboratory research. Audit in GLP Compliance Auditing is a critical component of GLP, ensuring adherence to established regulations and identifying areas for improvement. Audits can be internal (self-audit) or external (regulatory or third-party audits). Goals of Laboratory Quality Audit • Ensure compliance with GLP regulations. • Identify gaps and areas for improvement. • Validate data integrity and accuracy. • Enhance operational efficiency. • Prevent regulatory penalties and study disqualification. Audit Tools in GLP Laboratories use various audit tools to assess compliance, including: • Checklists and self-assessments • Internal quality audits • Electronic data tracking systems • Third-party inspections • Root cause analysis • Corrective and preventive action (CAPA) plans Future of GLP Regulations
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Dr. Smita Kumbhar
53 slides252 views
abdominalwalldefects n.pptx child health by Pooja Rani, has 22 slides with 18 views.abdominal wall defect
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CROUP.pdf FOR NURSING STUDENTS CREATED BY KIRAN KARETHA by KIRAN KARETHA, has 4 slides with 11 views. Croup is a common childhood illness characterized by swelling in the airway (larynx, Trachea and bronchi), leading to a distinctive barking cough and difficulty in breathing, often with a high-pitched, noisy sound called stridor when inhaling.  It is also known as laryngotracheobronchitis. THE WESTLEY SCORE: classification of croup severity SCORING SYSTEM:  A total score of < 2 indicates mild croup.  A total score of 3-5 is classifies as moderate croup.  A total score of 6-11 indicates severe croup.  A total score of >12 indicates impending respiratory failure.  The score ranges from 0-17. MANAGEMENT:  Supportive care including intravenous fluids to maintain hydration and oxygen inhalation to relieve hypoxia has to be given.  A single dose of dexamethasone 0.6mg/kg may decrease severity and duration of illness.  Inhalation of epinephrine may decrease the symptoms of stridor and respiratory distress immediately. PREVENTION:  Many cases of croup have been prevented by immunization for influenza and diphtheria.
CROUP.pdf FOR NURSING STUDENTS CREATED BY KIRAN KARETHACROUP.pdf FOR NURSING STUDENTS CREATED BY KIRAN KARETHA
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The-Power-of-Mindfulness-and-Meditation. by oziasrondonc, has 20 slides with 117 views.In this presentation, explore the transformative power of mindfulness and meditation in promoting mental clarity, reducing stress, and enhancing overall well-being. Learn how these practices can help you achieve a balanced, focused, and calm mind, leading to improved emotional health and increased productivity. Discover practical techniques to incorporate mindfulness and meditation into your daily routine for lasting positive effects on your life.
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1. Physiologic Model of Spatial Vision and Retinal Sampling.pptx by GauriSShrestha, has 44 slides with 12 views.rod and cones, bipolar cells, horizontal cells, amacrine cells, ganglion cells, spatial summation and resolution, retinal sampling, spatial tunning, receptive fields of retinal neural cells, retinal potentials, Ricco's law, spatial antagonism, mach band, fourier analysing of visual system
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Understanding-Seizures-and-Epilepsy-Management.pptx by Dr Ankush goyal, has 8 slides with 237 views.Epilepsy and Its Management Introduction Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures. It affects millions of people worldwide, cutting across all age groups and ethnicities. Seizures result from excessive and abnormal cortical nerve cell activity in the brain, leading to temporary changes in movement, sensation, behavior, or consciousness. This document provides a comprehensive overview of epilepsy, including its causes, classification, symptoms, diagnosis, and management strategies. Causes of Epilepsy Epilepsy can arise due to multiple factors, including genetic predisposition, brain injuries, infections, or developmental disorders. Some common causes include: Genetic Factors: Certain types of epilepsy have a hereditary component, suggesting that genetic mutations may contribute to its development. Brain Trauma: Head injuries from accidents or sports activities can lead to epilepsy. Stroke and Vascular Diseases: Stroke, which reduces oxygen supply to the brain, is a leading cause of epilepsy in older adults. Infections: Conditions such as meningitis, encephalitis, and neurocysticercosis can trigger epilepsy. Developmental Disorders: Disorders such as autism and neurofibromatosis have been linked to epilepsy. Tumors and Structural Abnormalities: Brain tumors and congenital malformations can also lead to epileptic seizures. Classification of Epilepsy The International League Against Epilepsy (ILAE) classifies epilepsy based on the nature of seizures and their origin in the brain: Focal (Partial) Seizures: Originate in one part of the brain and can be simple (without loss of consciousness) or complex (with impaired consciousness). Generalized Seizures: Involve both hemispheres of the brain and include types such as absence, tonic-clonic, myoclonic, and atonic seizures. Unknown Onset Seizures: When the starting point of the seizure is unclear. Epilepsy Syndromes: Specific syndromes such as Lennox-Gastaut syndrome, Dravet syndrome, and Juvenile Myoclonic Epilepsy have distinct features and management strategies. Symptoms of Epilepsy The clinical manifestations of epilepsy depend on the type of seizure and the brain region involved. Symptoms may include: Temporary confusion or staring spells Uncontrollable jerking movements (convulsions) Loss of consciousness or awareness Sensory disturbances such as tingling or hallucinations Emotional changes, anxiety, or déjà vu Diagnosis of Epilepsy A thorough medical evaluation is necessary to diagnose epilepsy accurately. The diagnostic process includes: Medical History and Physical Examination: A detailed history of seizure episodes, triggers, and associated conditions is crucial. Electroencephalogram (EEG): Measures electrical activity in the brain and identifies abnormal patterns suggestive of epilepsy. Neuroimaging (MRI, CT Scan): Detects structural abnormalities, tumors, or brain injuries. Blood Tests: Helps rule out metabolic or i
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Understanding-Seizures-and-Epilepsy-Management.pptx
Dr Ankush goyal
8 slides237 views
PARKINSON’S USMLE style question by dr ankush goyal by Dr Ankush goyal, has 43 slides with 292 views.Parkinsonism refers to a clinical syndrome characterized by a combination of motor and non-motor symptoms that resemble Parkinson’s disease (PD). It results from dysfunction in the basal ganglia, particularly due to dopamine deficiency in the substantia nigra. Key Features of Parkinsonism: 1. Bradykinesia – Slowness of movement with difficulty in initiating and executing voluntary movements. 2. Rigidity – Increased muscle tone, presenting as either: Lead-pipe rigidity (uniform resistance) Cogwheel rigidity (intermittent resistance with a ratchet-like quality) 3. Tremor – Resting tremor, typically "pill-rolling" (4-6 Hz), that improves with movement. 4. Postural Instability – Impaired balance leading to a higher risk of falls. Causes of Parkinsonism: 1. Idiopathic Parkinson’s Disease (PD) – The most common cause, due to progressive degeneration of dopaminergic neurons in the substantia nigra. 2. Drug-Induced Parkinsonism – Caused by dopamine-blocking agents (e.g., antipsychotics, metoclopramide, reserpine). 3. Atypical Parkinsonian Syndromes (Parkinson-plus syndromes) – Progressive conditions with additional features beyond classic Parkinsonism, such as: Multiple System Atrophy (MSA) Progressive Supranuclear Palsy (PSP) Corticobasal Degeneration (CBD) Dementia with Lewy Bodies (DLB) 4. Vascular Parkinsonism – Due to multiple small strokes affecting the basal ganglia. 5. Toxic or Metabolic Causes – Includes manganese poisoning, carbon monoxide exposure, Wilson’s disease. 6. Post-Encephalitic Parkinsonism – Rare, seen in survivors of encephalitis lethargica. Diagnosis: Clinical Evaluation – Based on cardinal motor symptoms. Response to Levodopa – Helps differentiate PD from other causes. Neuroimaging (MRI, DaTscan) – Useful in atypical cases. Management: Pharmacological Treatment: Levodopa (with carbidopa) Dopamine agonists (pramipexole, ropinirole) MAO-B inhibitors (selegiline, rasagiline) COMT inhibitors (entacapone) Anticholinergics (for tremors) Non-Pharmacological Treatment: Physiotherapy, speech therapy Deep Brain Stimulation (DBS) in selected cases
PARKINSON’S USMLE style question by dr ankush goyalPARKINSON’S USMLE style question by dr ankush goyal
PARKINSON’S USMLE style question by dr ankush goyal
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Integumentary System By Baasir Umair.pdf by Baasir Umair Khattak, has 78 slides with 86 views.The integumentary system is the largest organ system of the human body, serving as the body's first line of defense against environmental hazards. It includes the skin, hair, nails, glands, and sensory receptors. This system plays a vital role in protection, thermoregulation, sensation, excretion, and vitamin D synthesis. Understanding its structure and function is crucial for comprehending how the body interacts with its surroundings. Structure of the Integumentary System The integumentary system comprises two main components: The Skin (Cutaneous Membrane) Accessory Structures (Hair, Nails, and Glands) The Skin The skin, also called the cutaneous membrane, consists of three primary layers: 1. Epidermis The epidermis is the outermost layer of the skin, composed of stratified squamous epithelium. It lacks blood vessels and is primarily made of keratinocytes, which produce the protective protein keratin. Other important cells in the epidermis include: Melanocytes – produce melanin, which protects against UV radiation. Langerhans cells – involved in immune response. Merkel cells – associated with sensory neurons for touch perception. The epidermis has five distinct layers (from deep to superficial): Stratum basale (germinativum) – contains basal cells responsible for generating new keratinocytes. Stratum spinosum – provides structural integrity. Stratum granulosum – where keratinization begins. Stratum lucidum – found only in thick skin (palms and soles). Stratum corneum – the outermost layer made of dead keratinized cells. 2. Dermis The dermis is the thicker, connective tissue layer beneath the epidermis. It consists of collagen and elastic fibers, providing strength and flexibility. The dermis has two layers: Papillary Layer – composed of loose areolar connective tissue; contains dermal papillae, capillaries, and sensory receptors. Reticular Layer – made of dense irregular connective tissue; contains sweat glands, hair follicles, and blood vessels. 3. Hypodermis (Subcutaneous Layer) The hypodermis is a layer of adipose and connective tissue that insulates the body, stores energy, and provides cushioning. It connects the skin to underlying muscles and bones. Functions of the Integumentary System The skin performs several essential functions, including: 1. Protection The skin acts as a physical barrier against microorganisms, dehydration, UV radiation, and harmful chemicals. The acid mantle (low pH) of the skin inhibits bacterial growth. 2. Thermoregulation The skin helps maintain body temperature through: Sweating (eccrine and apocrine glands) – evaporative cooling. Vasodilation – blood vessels widen to release heat. Vasoconstriction – blood vessels narrow to retain heat. Goosebumps (arrector pili muscles) – create an insulating layer. 3. Sensation The skin contains specialized sensory receptors: Meissner’s corpuscles – detect light touch. Pacinian corpuscles – sense deep pressure and vibration. Merkel cells –
Integumentary System By Baasir Umair.pdfIntegumentary System By Baasir Umair.pdf
Integumentary System By Baasir Umair.pdf
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Growth and development milestone 7 months .pptxGrowth and development milestone 7 months .pptx
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Good Laboratory Practices (GLP) Ensuring Quality and Compliance.pptx by Dr. Smita Kumbhar, has 53 slides with 252 views.Good Laboratory Practices (GLP): Ensuring Quality and Compliance Good Laboratory Practices (GLP) is a set of principles intended to ensure the quality, integrity, and reliability of non-clinical laboratory studies that support research and regulatory submissions. These guidelines are critical in the pharmaceutical, biotechnological, chemical, and environmental sectors, ensuring that laboratory-generated data are reproducible, credible, and internationally accepted. GLP standards primarily apply to safety studies involving pharmaceuticals, pesticides, food additives, and industrial chemicals. Regulatory agencies, including the USFDA, EMA, and OECD, enforce GLP compliance to maintain scientific rigor and public safety. USFDA GLP Regulations The U.S. Food and Drug Administration (USFDA) established Good Laboratory Practice regulations under 21 CFR Part 58. These regulations outline responsibilities for study directors, testing facilities, and personnel to maintain quality and integrity in non-clinical laboratory studies. The regulations cover various aspects, including study conduct, reporting, and archiving, ensuring consistency and accuracy in laboratory research. Controlling the GLP Inspection Process Regulatory authorities conduct inspections to verify GLP compliance. Laboratories must prepare for inspections by: • Maintaining up-to-date documentation. • Conducting internal audits. • Ensuring personnel training and awareness. • Implementing corrective actions for non-compliance. Regulatory inspections typically assess laboratory infrastructure, personnel competence, study documentation, and adherence to protocols. Laboratories must demonstrate transparency and proactive quality control measures. Documentation in GLP Accurate and comprehensive documentation is crucial in GLP compliance. Key documentation elements include: • Study protocols • Standard operating procedures (SOPs) • Raw data records • Analytical reports • Audit reports • Equipment calibration records • Archiving and retention policies Proper documentation ensures traceability, accountability, and reliability in laboratory research. Audit in GLP Compliance Auditing is a critical component of GLP, ensuring adherence to established regulations and identifying areas for improvement. Audits can be internal (self-audit) or external (regulatory or third-party audits). Goals of Laboratory Quality Audit • Ensure compliance with GLP regulations. • Identify gaps and areas for improvement. • Validate data integrity and accuracy. • Enhance operational efficiency. • Prevent regulatory penalties and study disqualification. Audit Tools in GLP Laboratories use various audit tools to assess compliance, including: • Checklists and self-assessments • Internal quality audits • Electronic data tracking systems • Third-party inspections • Root cause analysis • Corrective and preventive action (CAPA) plans Future of GLP Regulations
Good Laboratory Practices (GLP) Ensuring Quality and Compliance.pptxGood Laboratory Practices (GLP) Ensuring Quality and Compliance.pptx
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2024 State of Marketing Report – by Hubspot by Marius Sescu, has 43 slides with 118891 views.https://www.hubspot.com/state-of-marketing · Scaling relationships and proving ROI · Social media is the place for search, sales, and service · Authentic influencer partnerships fuel brand growth · The strongest connections happen via call, click, chat, and camera. · Time saved with AI leads to more creative work · Seeking: A single source of truth · TLDR; Get on social, try AI, and align your systems. · More human marketing, powered by robots
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5 Public speaking tips from TED - Visualized summary by SpeakerHub, has 16 slides with 18616 views.From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world. With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively. The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage. Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience. See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers See the original article on Forbes here: http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
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